Mendelian Genetics and Genetic Analysis Tools
Name: _______________________________
Print this lab, follow directions and answer all questions neatly in the worksheet that follows this lab. Once
completed, save the LAB_WORK SHEET with your last name & submit within Work2Do tab. Be sure to save your
document as LASTNAME_lab7. My last name is Ashraf, so my file would be named Ashraf_lab7.
Directions
This lab is an on‐line lab. Read the text below and answer the questions
within each part in a word processor document. Mendelian Genetics
Gregor Mendel was a biologist now known as the "Father of genetics,"
(both because he was a monk and because he was the first to
quantitatively determine how various genetic traits were passed on from
parents to offspring). Although he could not have known about DNA and
genes at the time, his conclusions about a number of crossbreeding
studies he carried out (as described in chapter 10 of your textbook) were
vital to the development of genetics. Some years after Mendel, Dr.
Reginald Crundall Punnett developed a graphical tool, the Punnett square,
for predicting the genotypes of offspring from cross‐breeding
experiments involving genes that operated like those Mendel studied.
Part 1: Complete the following brief exercise to familiarize yourself with Punnett squares. Follow the link and read the
University of Arizona's Biology Project's tutorial on how to set up a Punnett square:
A.
B. Answer Questions 1 & 2 on the lab write‐up worksheet (write answers there—not here!) after you have
completed the tutorial to test your understanding.
Part 2: Blood Typing human blood (types A, B, AB, and O) is an example of a trait that (mainly) works according to
Mendelian genetics. For instance, there are dominant traits (A and B) and a recessive trait (O) that are the result
of specific alleles (note: the A and B alleles are co‐dominant so that, when paired, they produce type AB blood).
Additionally, there is another component to blood typing—the Rh factor—that comes into play, producing
‐
+
positive and negative blood (e.g. A
, B
, etc.). The following tutorials will assist you in learning about how blood
types arise and how to determine them using antibodies. Once you have mastered the genetics behind blood
types, you can test your skills on cyber‐patients who have recently been in a car crash and need blood!
Go to University of Arizona's Biology Project tutorial on blood types and read the "Introduction" page:
A.
B. Click of the words "Human ABO markers" on the left side of the screen. Read about the ABO markers.
C. Next, click on "Blood types and genotypes?" on the left side of the screen. Read about how blood type
genotypes result in different blood type phenotypes.
D. Click on the new “Blood type and Rh Factor calculator” on the left side of the screen and determine both the
possible blood type of the child and the possible blood type of the parents.
E. Click on the words "Rh factor" on the left side of the screen. Read about the Rh factor and how it influences
blood types.
F. Answer Questions 3, 4, 5, 6, 7, 8 on your worksheet (not here!)
Part 3: Now, let's test your blood typing skills! Go to the following web site located in the Nobel e‐Museum (from the
Nobel foundation ‐ as in "Nobel prize" ‐ in Sweden):