Dna Paper Model

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Build a Paper Model of DNA
Fill in the names of the bases on the model shown to the
right, or use the detailed model that shows all the atoms in
each nucleotide (back side of paper).
1
2
3
Fold dotted grey lines so they are
Cut out the model.
Fold all long creases first. Solid
grey lines should be visible on
hidden in the crease.
the crease.
4
5
6
Tuck the other backbone flaps
Fold the backbones so the model
Fold the paper in half so that the
(with 5’ at the top) one over the
is flat. Fold the horizonal and
backbone (with 3’ written at the
other, so your model looks like the
diagonal lines like a fan (solid
top) pops out.
on in the picture.
lines should be visible on the
crease, dotted lines on the inside).
7
8
9
Your model should look like this
Pull the model open, and pop out
Your finished model is a right-
when all lines have been folded.
the backbones on the sides.
handed double helix. Use the tabs
to connect several models to
make longer strands.
About DNA
DNA is perfect for the storage and readout of genetic information, which is stored in the way
the bases match one another on opposite sides of the double helix. Adenine (A) pairs with
thymine (T), and guanine (G) with cytosine (C), with each pair forming a set of complemen-
tary hydrogen bonds.
The all-atom model (shown on the second side) has the sequence C-G-C-T-T-A-A-G-C-G.
Notice that this sequence is palindromic: if you take one chain and flip it around, it will
form the proper base pairs with another copy of the chain. Add your own base pairs in the
model to the right…but be sure to pair them up properly! The edges of the base pairs are
exposed in the two grooves of the double helix: the wider major groove and the narrower
minor groove. These edges are also used to carry information that is read by proteins that
interact with the double helix.
Go to to:
• READ the Molecule of the Month on DNA
• DOWNLOAD additional copies of this model, and WATCH a video
demonstration of how to build it (Learn > Paper models)
PDB-101 is the educational portal of RCSB Protein Data Bank ()

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