Energy Sources For Muscular Contraction Worksheet

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Energy Sources for Muscular Contraction
Introduction:
Energy is released when adenosine triphosphate (ATP) is split into adenosine
diphosphate and phosphoric acid. The energy given up in this reaction is what powers
muscular contractions. Since there is no store of ATP in the body, it must be synthesized
continuously. This resynthesis of ATP from ADP and phosphoric acid is supplied by the
energy released in the splitting of creatine phosphate (CP). But creatine phosphate is also
in short supply and must be resynthesized continuously. There are two sources of energy
for the resynthesis of ATP and CP. These two sources are (1) the combustion of food as
measured by the consumption of oxygen, and (2) glycolysis, the breakdown of glycogen
resulting in the formation of lactic acid. Lactic acid can be reconstituted to glycogen with
energy input from food combustion.
Thus there are three reactions which produce energy;
1. splitting of ATP and CP
2. food combustion
3. glycolysis,
and two reactions which require energy;
1. ATP and CP resynthesis
2. glycogen resynthesis.
For moderate muscular energy requirements, the combustion of food can supply the
energy requirements for the ATP and CP synthesis, and this can be measured by the
consumption of oxygen (oxidation). Tests have shown that energy yield from oxidation
is about five calories per milliliter of oxygen consumed. The rate of the heart beat has
been shown to be a good measure of the rate of oxygen consumption.
For moderate steady exercise, the energy supplied to the muscles can be provided by
oxidation up to a maximum of about 220 calories per minute per kilogram of weight.
When this energy requirement is exceeded, then energy must be supplied by glycolysis,
and the resulting formation of lactic acid. The energy supplied by glycolysis is about 230
calories per gram of lactic acid produced, up to a maximum of about 50 grams. From this
information, one can calculate the rate at which work (work per unit time is defined as
power, measured in Watts) can be performed by the muscles if the energy is supplied
only by oxidation or by both oxidation and glycolysis. If one exceeds the power supplied
by 220 calories per minute per kilogram of weight, then lactic acid formation will occur,
and it will take time to resynthesize the glycogen after the work is complete. Thus more
rest is required after strenuous exercise because the lactic acid that has been built up must
be resynthesized to glycogen. In strenuous exercise you build up an energy deficit
(oxygen debt) that must be repaid by rapid breathing. The larger the oxygen debt
incurred, the longer it will take to recover.
In this experiment you will calculate the rate at which you can perform a particular type
of exercise, and how much lactic acid will be produced for different exercise rates.

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