Blood Typing Lab Page 2

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Blood Typing Lab:
Background: There are protein markers, called antigens, on the surface of red blood cells. You inherit these proteins,
which define your blood type, from your parents. Blood type is particularly important when people give or receive blood
for transfusions.
The immune system uses different types of proteins to fight off foreign cells. Antibodies are one of these types of
proteins. Antibodies might cause foreign cells, such as foreign red blood cells, to clump together. If you receive blood
with a protein marker different from your own, your immune system will use antibodies as part of its attack against the
foreign blood cells. The antibodies will cause the red blood cells to clump together. Blood cannot flow through the
vessels, and death can result.
There are two protein markers, A and B, and four blood groups, A, B, AB, and O, known as the ABO blood group. Type O
blood has no protein markers and can be donated to a person with any other blood type. A person with Type O blood
however, can only accept Type O blood.
Before a patient receives a transfusion, blood must be matched for both the ABO group and the Rh group.
Part 1 -
1. Go to -
2. Click on “Educational” (it’s near the top of the page in the menu bar)
3. To the right side, click “The Blood Typing Game”
4. Click “Play blood typing game”.
5. Choose quick game “random”
6. Choose a patient
7. Click on the syringe and then hold it to the patients arm to take some blood. Hover the syringe over each of the
three test tubes to add blood to them.
8. Record what happens in each of the test tubes in the chart below.
Tube A (Anti –A)
Tube B (Anti-B)
Tube Rh
Blood type of
Blood patient can receive
(Anti-Rh)
patient
Patient 1
Patient 2
Patient 3
Part 2
1. Go to . Click on high school science. Click on California and click go. Choose Biology 2010. Under
“labs” – choose virtual lab, then choose blood typing.
https://
2. Read the problem:
a. What must doctors do before the transfusion? _______________________________________________
3. Follow the steps and answer the questions:
a. What is the function of the following
i. Anti – A serum __________________________________________________________________
ii. Anti – B serum __________________________________________________________________
iii. Anti – Rh serum ________________________________________________________________
4. Click on Lab notebook and read the “additional information” section:
a. What are protein markers? ______________________________________________________________
b. Where do you get them from? _______________________________________________
c. What are the four main blood types? _______________________________________________
d. What does the immune system create to fight against foreign blood cells? ________________________

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