Biology Blood Types And Heredity Page 2

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Student Sheet
name__________________________
Title: Blood Types and Heredity
Introduction: British physician James Blundell recorded the first blood
transfusions in 1825. About half of his patients benefited from them but many
had severe reactions and several died. Would you have volunteered for a
transfusion given these odds? After careful investigation it was discovered that
blood cells contain surface proteins on the cell membrane that identify 4 different
blood types. A has “A” surface proteins, B has “B” surface proteins, AB has both
“A” and “B” surface proteins and O blood has no marker proteins on the cell
membrane. Add the surface proteins to the drawings of blood cells below:
A
B
AB
O
Later experiments showed that not all blood types can be mixed together without
a clumping reaction that occurs when a “foreign invader” enters a human body.
Our immune system “knows” which cells belong in our body. It is able to
recognize intruding cells and kill them. Some blood types are recognized as
foreign and the clumping reactions occur that may harm the patient.
In this activity, you will find out which types of blood are safe to transfuse into
people with different blood types. You will also see how blood types are
genetically determined.
Prediction: Which type of blood might be safe to put in anyone?
Materials: 20 ml red water , 20 ml green water, 20 ml clear water, 5 test tubes,
test tube rack, 25 ml graduated cylinder, beaker, medicine dropper or pipette
Procedures:
1. Use this key to the blood types and colors:
A= red water
B=green water
AB=red + green water=brown water
O=clear water

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