Non-Mendelian Genetics High School Biology Worksheet With Answers Page 3

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11. Fill in the table below based in the information in Figure B.
Questions about Pedigree in Figure B
Answer
a. Number of Generations
3
b. Number of men w/hemophilia
4
c. Number of women with normal blood clotting
10
d. Number of marriages
6
e. Number of men with the genotype X
Y
5
N
f. Number of women with genotype X
X
1
n
n
5
g. Number of single women
h. Number of people that never married
8
i. Number of women with genotype X
X
4
N
?
j. Number of couple with only one child
1 (5-6 Gen 2)
Analysis and Conclusion:
1. What are ALL the possible genotypes in a pedigree of sex-linked traits?
_4-Female 2 - Male_________________________________________________________________
N
n
N
N
n
n
N
n
N
?
X
Y, X
Y
X
X
, X
X
, X
X
, X
X
2. Why do males usually inherit sex-linked diseases such as hemophilia?
They only have one X chromosomes, females have two. Females have a good chance of
inheriting a “good” copy of the gene. Males lack a second opportunity to cover a
“defective” gene on the X chromosome.
3. How can you determine the genotype of a female that does NOT exhibit a sex-linked disease (i.e. genotype
could be X
X
, X
X
, or X
X
)?
N
N
N
n
N
?
It’s a puzzle! Look at their parents and offspring for clues. Father’s give the disease to
their daughters, mother’s give the disease to their sons. Sons get it from their mothers,
daughters can get the gene from either parent.
3

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