Lab: Using Blood Tests To Identify Criminals And Babies - Anatomy And Physiology Worksheet Page 2

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Explanation of results: Normally, our bodies do not make antibodies against any molecules
that are part of our own bodies. Thus, antibodies help to defend against invading viruses and
bacteria, but normally antibodies do not attack our own body cells. For example, people with
Type A blood do not make antibodies against the Type A antigen, which is present on their red
blood cells. However, they do make antibodies against the Type B antigen (called anti-B
antibodies).
4. Test your understanding of blood groups by filling in the blanks in the chart below.
Blood group A
If you belong to the blood group A, you have A
antigens on the surface of your red blood cells
and ________ antibodies in your blood.
Blood group B
If you belong to the blood group B, you have B
antigens on the surface of your red blood cells
and ________ antibodies in your blood.
Blood group AB
If you belong to the blood group AB, you have
both A and B antigens on the surface of your red
blood cells and no anti-A or
anti-B antibodies in your blood.
Blood group O
If you belong to the blood group O, you have
neither A nor B antigens on the surface of your
red blood cells, but you have both
________ and ________ antibodies in your
blood.
Blood transfusions — Who can receive blood from whom?
If you are given a blood transfusion that does not
match your blood type, antibodies present in your
blood can react with the antigens present on the
donated red blood cells. For example, if a person
who has Type A blood is given a Type B blood
transfusion, then this person's anti-B antibodies
will react with the Type B antigens on the donated
red blood cells and cause a harmful reaction. This
transfusion reaction can cause the donated red
blood cells to burst and/or clump together and
block blood vessels.
Transfusion reactions can be fatal. To prevent this from happening, doctors test whether a person's
blood is compatible with the donated blood before they give a transfusion. A person can only be given
donated blood with red blood cells that do not have any antigen that can react with the antibodies in
the person's blood.

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