Screening Questionnaire Or Seasonal And H1n1 Influenza Injectable Vaccination Form Page 2

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Information for Health Professionals about the Screening Questionnaire
for Seasonal and H1N1 Influenza Injectable Vaccination
Are you interested in knowing why we included a certain question on the Screening
Questionnaire? If so, read the information below. If you want to find out even more, consult the
sources listed at the bottom of this page.
1. Is the person to be vaccinated sick today?
3. Has the person to be vaccinated ever had a
There is no evidence that acute illness reduces
serious reaction to influenza vaccine in the
vaccine efficacy or increases vaccine adverse
past?
events. Persons with an acute febrile illness usually
Patients reporting a serious reaction to a previous
should not be vaccinated until their symptoms have
dose of inactivated influenza vaccine should be
improved. Minor illnesses with or without fever do
asked to describe their symptoms. Immediate—
not contraindicate use of influenza vaccine. Do not
presumably allergic—reactions are usually a
withhold vaccination if a person is taking antibiotics.
contraindication to further vaccination against
influenza.
2. Does the person to be vaccinated have an
allergy to eggs or to a component of the
Fever, malaise, myalgia, and other systemic
vaccine?
symptoms most often affect persons who are first-
Allergic reactions to any vaccine component can
time vaccinees. These mild-to-moderate local
occur. The majority of reactions probably are
reactions are not a contraindication to future
caused by residual egg protein. Although current
vaccination. Also, red eyes or mild upper facial
influenza vaccines contain only a limited quantity of
swelling following vaccination with inactivated
egg protein, this protein can induce immediate
injectable influenza vaccine is most likely a
allergic reactions among persons who have severe
coincidental event and not related to the vaccine;
egg allergy. If a person can eat eggs, they can
these persons can receive injectable vaccine
receive inactivated influenza vaccine. However,
without further evaluation.
persons who have experienced an anaphylactic
reaction (e.g., hives, swelling of the lips or tongue,
4. Has the person to be vaccinated ever had
acute respiratory distress, or collapse) after eating
Guillain-Barré syndrome?
eggs should consult a physician for appropriate
It is prudent to avoid vaccinating persons who are
evaluation to help determine if vaccine should be
not at high risk for severe influenza complications
but who are known to have developed Guillain-
administered. Persons who have documented
immunoglobulin E (IgE)-mediated hypersensitivity
Barré syndrome (GBS) within 6 weeks after
to eggs, including those who have had occupational
receiving a previous influenza vaccination. As an
asthma or other allergic responses to egg protein,
alternative, physicians might consider using
might also be at increased risk for allergic reactions
influenza antiviral chemoprophylaxis for these
to influenza vaccine. Consultation with a physician
persons. Although data are limited, the established
should be considered. Protocols have been
benefits of influenza vaccination for the majority of
published for safely administering influenza vaccine
persons who have a history of GBS, and who are at
to persons with egg allergies (see source 3).
high risk for severe complications from influenza,
justify yearly vaccination.
FluZone (sanofi pasteur) contains gelatin as a
stabilizer; therefore a history of anaphylactic
______________________
reaction to gelatin is a contraindication. Some
Sources:
inactivated influenza vaccines contain thimerosal as
1. CDC. Epidemiology & Prevention of Vaccine-Preventable
a preservative. Most persons with sensitivity to
Diseases, WL Atkinson et al., editors, at
thimerosal, such as that found in contact lens
pubs/pinkbook.
solution, do not experience reactions to thimerosal
2. CDC. “General Recommendations on Immunization:
Recommendations of the Advisory Committee on Immunization
administered as a component of vaccines. Check
Practices (ACIP)” at pubs/acip-list.htm.
the package insert at
3. CDC. “Prevention and Control of Influenza—
packageinserts
for a list of the vaccine components
Recommendations of ACIP” at
(i.e., excipients and culture media) used in the
vaccination.
4. CDC. “Use of Influenza A (H1N1) 2009 Monovalent Vaccine”
production of the vaccine, or go to
at
vaccines/pubs/pinkbook/downloads/appendices/B/e
xcipient-table-2.pdf.
Adapted by MDPH from Screening Questionnaire for Injectable Vaccination from the Immunization Action
Coalition
(9-09)--

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