High Risk Medications List - 2017 Page 4
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7High risk medications
U
pdated May 2017
*
Alternatives When Diagnosis is NOT KNOWN
Classification
Drug name
Risk
If diagnosis is known - refer to FER Alternatives document
For neuropathic pain:
1
capsaicin topical
OTC
duloxetine (generic for Cymbalta)
FETZIMA
PRISTIQ
venlafaxine (generic for Effexor)
venlafaxine ER (generic for Effexor XR)
gabapentin
desvenlafaxine ER
LYRICA
lidocaine 5% patch (for diabetic neuropathy, postherpetic neuralgia,
and cancer-related neuropathy only)
For epilepsy:
lamotrigine (generic for Lamictal)
levetiracetam (generic for Keppra)
other anticonvulsants
Antipsychotics, first-
Increased risk of stroke, cognitive decline, and mortality in
For schizophrenia, use nonanticholinergic antipsychotics:
thioridazine (MELLARIL)
generation
persons with dementia. Avoid use for behavioral problems
aripiprazole (generic for Abilify)
(conventional)
related to dementia or delirium unless there is threat of
haloperidol tablet (generic for Haldol)
substantial harm to self or others.
risperidone (generic for Risperdal)
risperidone ODT (generic for Risperdal M-Tab)
thiothixene (generic for Navane)
ziprasidone (generic for Geodon)
Barbiturates
amobarbital (AMYTAL)
High rate of physical dependence, tolerance to sleep benefits,
For epilepsy:
and a greater risk of overdose at low doses
butabarbital (BUTISOL)
lamotrigine (generic for Lamictal)
butalbital (FIORICET, FIORINAL, ETC.)
levetiracetam (generic for Keppra)
pentobarbital (NEMBUTAL)
other anticonvulsants
phenobarbital (LUMINAL)
secobarbital (SECONAL)
* Alternatives are recommended by The American Geriatrics Society, unless otherwise noted. Alternatives are not diagnosis-specific.
¹ OTC (over-the-counter) drugs are not covered by Medicare Part D
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