Chemistry Of Macromolecules Course Outline Template (Page 2 of 2) in pdf

Chemistry Of Macromolecules Course Outline Template Page 2

steady state approximation, Enzyme catalysed reactions and the

MichaelisMenten reactions

Modifying the MichaelisMenten equation for enzymatic reactions in

the presence of different types of inhibitors;LineweaverBurk, Hanes

and EadieHofstee plots and their significance.

10.

Quantum mechanics: Understanding the break between classical

and quantum physics. Introduction to the idea of the waveparticle

and Schrö d inger’s equation. Significance of boundary conditions for

quantization. The idea of wave functions and orbitals. A particle in

one and three dimensional box and its implications for the

understanding of the Hatom. Energy and wavefunctions of the Hlike

atoms. Radial distribution functions. Molecular orbital theory and

orbital hybridization.

11.

Physical

organic

chemistry:

Conjugation,

aromaticity

and

resonance. Inductive and field effects. Hydrogen bonding and

hydrophobicity.

12.

Some important reaction mechanisms in organic chemistry: SN1,

SN2, E1, E2 and electrophilic addition reactions, free radicals and

singlet oxygen production

13.

Common reaction mechanisms encountered in biological reactions;

peptide bond formation, oligonucleotide and oligosaccharide

synthesis, disulphide bonds, group-specific chemical modifications

for amino acids

14.

Basic principles of bioinorganic chemistry: Coordination bonds and

metal- ligand interactions. Metalloproteins and metalloenzymes.

Role of metal ions in biological systems.

Chemistry Of Macromolecules Course Outline Template Page 2