Amino Acid Sequences Worksheet

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Amino Acid Sequences – Finding Similarities Worksheet
Name ____________________________________
Instructions:
The following Data Table 1 shows the amino acids found in selected sites in hemoglobin
of different vertebrates. Examine the chart for differences between humans and other
organisms.
1. Count the numbers of molecules of each amino acid in human hemoglobin.
Record these totals in the appropriate column of Data Table 2.
2. Count the number of molecules of each amino acid of other vertebrates’
hemoglobin. Record these totals in the appropriate columns of Data Table 2.
3. Going from left to right, note the position of each amino acid. Count the number
of similarities in the amino acid positions in human hemoglobin as compared with
the hemoglobin of the other vertebrates in Data Table 1. Record your observations
in Data Table 3.
4. Reexamine Data Table 1 and count the numbers of differences in the amino acid
positions in human hemoglobin as compared with the hemoglobin of the other
vertebrates in Data Table 1. Record observations in Data Table 3.
Data Table 1: Selected Amino Acid Positions in the Hemoglobin of some vertebrates
Human
V K A H G K K V L G A F S D G L A H L D
Chimpanzee
V K A H G K K V L G A F S D G L A H L D
Gorilla
V K A H G K K V L G A F S D G L A H L D
Baboon
V K A H G K K V L G A F S D G L N H L D
Lemur
V K A H G K K V L T A F S E G L H H L D
Dog
V K A H G K K V L N S F S D G L K N L D
Chicken
V R A H G K K V L T S F G D A V K N L D
Frog
V L A H G E K V L A A I G E G L K H P E

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