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Portland Continuous Intravenous Insulin Protocol ICU TARGET BLOOD GLUCOSE 100 to 150mg/dl
Version 2008.1: ICU PHASE 2
ICU: May titrate Insulin Infusion between 0-30 units /hour using the following as GUIDELINES to rapidly (within 3 hrs) achieve and maintain BG in target
range (100-150). Round insulin Infusion to the nearest tenth of a unit (0.1) when necessary.
Blood
Note: If ANY BG is less than 40mg/dl or greater than 450mg/dl, obtain confirmatory laboratory BG
Glucose (BG)
Action:
Less Than 60
Stop Insulin:
If not alert or if NPO: give 15 ml of D50W IV; If < 40 give 25 ml of D50W IV
If alert and taking PO give 8 ounces of juice PO OR 6 glucose tablets PO
Recheck BG every 30 minutes until greater than 90mg/dl
If next BG is < 50mg/dl: Double amount of previous treatment; If next BG is 50 – 65 mg/dl repeat treatment
& recheck BG in 30 minutes
When BG greater than 100mg/dl: Restart Insulin rate at 50% of previous rate
60 to 79
Stop Insulin:
If Previous BG greater than 110mg/dl OR if symptomatic from hypoglycemia:
º
If NPO: give 15 ml of D50W IV; <OR> IF taking PO: give 4-6 ounces of juice OR 3 glucose tablets PO.
Recheck BG every 30 minutes until greater than 90mg/dl
If next BG remains 60 - 79 mg/dl : Repeat previous treatment
When BG greater than 90mg/dl: Restart Insulin rate at 50% of previous rate
& recheck BG in 30 minutes
80 to 99
If greater than last test: Decrease rate by 0.3 units / Hour
If lower than last BG by more than 30 mg/dl: Stop drip & recheck BG in 30 minutes (see bold * order)
& recheck BG in 30 minutes
If lower than last BG by 15 – 30 mg/dl: Decrease rate by HALF (50%)
If lower than last BG by 7 – 14 mg/dl: Decrease rate by 0.5 Units / Hour
If equal to last BG or lower than last BG by less than 7 mg/dl: Decrease rate by 0.3 Units / Hour
&
*If infusion turned off, recheck BG in 30 min, when BG greater than 100mg/dl restart at 50% of previous rate
recheck BG in 30 minutes
Recheck BG every 30 minutes until greater than 90mg/dl
100 to 150
If higher than last BG by more than 10mg/dl: Increase rate by 0.5 Units / Hour
Target Range
If lower than last BG by more than 40 mg/dl: Stop drip & recheck BG in 30 minutes (see bold ** order)
EXCELLENT!
& recheck BG in 30 minutes
If lower than last BG by 21–40 mg/dl: Decrease rate by HALF (50%)
May titrate
If lower than last BG by 10-20mg/dl: Decrease rate by 0.5 Units / Hour
drip in ICU to
** If infusion turned off, recheck BG 30 min, if /when BG greater than 130 mg/dl restart at 50% of previous rate
maintain this
If within 10mg/dl of last BG same rate… unless the following applies:
range. See
FOR ANY BG in this range (even if within 10 mg/dl of last test) the following ALWAYS applies:
Suggestions:
º BG has consistently decreased each of last 4 measurements: Decrease rate by an additional 0.3 Units / Hour
º BG has consistently increased each of last 4 measurements: Increase rate by an additional 0.2 Units / Hour
151 to 175
If higher than last BG by more than 50mg/dl: Increase rate by 2 Units/Hour
If higher than last BG by 20 - 50mg/dl: Increase rate by 1 Unit / Hour
If higher than last BG by 0 - 20mg/dl: Increase rate by 0.5 Units / Hour
If lower than last BG by 1 - 20 mg/dl: Same rate
If lower than last BG by 21 - 40mg/dl: Decrease rate by 1 Unit / Hour
If lower than last BG by 41 – 60 mg/dl: Decrease rate by HALF (50%) and recheck BG in 30 minutes
If lower than last BG by more than 60 mg/dl: Stop drip & recheck BG in 30 minutes (see bold ** order below)
**If infusion turned off, recheck BG 30 min, if / when BG greater than 150mg/dl restart at 50% of previous rate
176 to 200
If higher than last BG by more than 30mg/dl: Increase rate by 2 Units/Hour & bolus with 3 units IV
If higher than last BG by 0 - 30mg/dl: Increase rate by 1 Unit / Hour & bolus with 2 units IV
If lower than last BG by 1 – 20: Increase rate by 1 Unit / Hour & bolus with 2 units IV
If lower than last BG by 21 to 50mg/dl: Same rate
If lower than last BG by 51 – 80mg/dl: Decrease rate by HALF (50%) and recheck BG in 30 minutes
If lower than last BG by more than 80mg/dl: Stop drip & recheck BG in 30 minutes (see bold ** order below)
Recheck BG in 30 minutes. Repeat BG every 30 minutes until less than 175mg/dl
**If infusion turned off, recheck BG 30 min, if / when BG greater than 150mg/dl restart at 50% of previous rate
201 to 225
If lower than last BG by more than 80mg/dl: Decrease rate by HALF (50%)
If lower than last BG by 30 –80mg/dl: Continue same rate
If lower than last BG by 0 – 30: Increase Insulin rate by 1 Unit / Hour & bolus with 2 units IV
If higher than last BG by 1- 20mg/dl: Increase Insulin rate by 2 Units / Hour & bolus with 4 units IV
If higher than last BG by more than 20mg/dl: Increase Insulin rate by 3 Units/Hour & bolus 6 units IV
Recheck BG in 30 minutes. Repeat BG every 30 minutes until less than 175mg/dl
226 to 275
If lower than last BG by more than 100 mg/dl: Decrease rate by HALF (50%)
If lower than last BG by 50 – 100 mg/dl: Continue same rate
If lower than last BG by less than 50mg/dl OR higher than last BG:
º BOLUS with 6 units Regular Insulin IV AND Increase Insulin rate by 2 Units / Hour
If BG remains 226 - 275 mg/dl and has not decreased after 3 consecutive increases in Insulin:
a.
Give DOUBLE previous IV BOLUS dose up to a maximum of 24 units AND
b.
DOUBLE Insulin drip rate -- up to a maximum of 20 units / hour
c.
If on 20 units/hour and no response after 4 maximum boluses – CALL MD for further orders
Recheck BG in 30 minutes. Repeat BG every 30 minutes until less than 175mg/dl
Greater than
If lower than last BG by more than 150 mg/dl: Decrease rate by HALF (50%)
275
If lower than last BG by 101-150mg/dl : Same rate
If lower than last BG by 0- 100mg/dl OR if higher than last BG:
º BOLUS with 10 Units Regular Insulin IV AND DOUBLE Insulin rate up to a maximum of 30 units / hour
If BG remains greater than 275 mg/dl and has not decreased after 3 consecutive increases in Insulin:
d.
Give DOUBLE previous IV BOLUS dose up to a maximum of 40 units AND
e.
DOUBLE Insulin drip rate -- up to a maximum of 30 units / hour
f.
If on 30 units/hour and no response after 4 maximum boluses – CALL MD for further orders
Recheck BG in 30 minutes. Repeat BG every 30 minutes until less than 175mg/dl
IF BG GREATER THAN 300 for 4 CONSECUTIVE READINGS: CALL MD FOR ADDITIONAL IV BOLUS ORDERS
Physician Signature___________________________________Date:__________Time:_________

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