Mendelian Genetics And Genetic Analysis Tools (Page 3 of 3) in pdf

Mendelian Genetics And Genetic Analysis Tools Page 3

For our analysis, we will be determining whether a genetic disorder is autosomal or sex‐linked, and whether the disorder

is dominant or recessive.

If you look at the pedigree chart above, you can see that the disorder affects males more often than females, and that it

has a high rate of frequency. These two clues lead to the conclusion that the disorder is probably sex‐linked (since it

appears to be gender‐dependent) and that it is dominant (since about 1/2 the total number of people are affected by

the disorder. Thus, our analysis of the genetic disorder above would be "Sex‐linked Dominant".

There are four possibilities for pedigrees using this method of analysis: Autosomal Dominant, Autosomal Recessive,

Sex‐linked Dominant (as was the case above), and Sex‐linked Recessive. Look at the following four pedigrees, and state

whether you think each disorder is Autosomal Dominant, Autosomal Recessive, Sex‐linked Dominant, or Sex‐linked

Recessive. Also, give a brief justiﬁcation for your choice.

Pedigree 3:

Pedigree 2:

Pedigree 4:

Pedigree 5:

Answer: Question 21 on the worksheet.

Hope you enjoyed the lab.

Be sure to send your word processor file to the instructor via Work2Do tab.

Mendelian Genetics And Genetic Analysis Tools Page 3