Pharmacology Drug Chart Page 16
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18Pharmacology Drug Chart Page 16
2+
ACTION
Causes the ultimate depletion of Norepinephrine
Mg
/ ATP
2+
in the adrenergic neuron
Dependent
Blocks the Mg
/ ATP Dependent transporter
Sympathetic function is greatly impaired
Transporter
from transporting Norepinephrine, Dopamine
Reserpine
May cause Bradycardia
and Serotonin from the cytoplasm into the
REPEAT
storage vesicles
THERAPEUTIC USES
Treatment of Hypertension
Vasodilators
Drug Name
Receptor
Therapeutic Uses
Adverse Effects
Atrial Dilation
Tachycardia
↓ TPR
GI discomfort
Hydralizine
Treatment of Hypertension
Hirsuitism
Atrial Dilation
Tachycardia
↓ TPR
GI discomfort
Minoxidil
Treatment of Hypertension
Hirsuitism
K+ Sparing Diuretics
Drug Name
Receptor
Therapeutic Uses
Adverse Effects
Competes with
Leads to Na Secretion and K Retention
Hyperkalemia
Aldosterone
Weak Diuretic
Spirolactene
Receptors
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