Pharmacology Drug Chart Page 17
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18Pharmacology Drug Chart Page 17
Autacoids
Drug Name
Receptor
Therapeutic Uses
Adverse Effects
Abortion
With Alprostadil there is pain at the site of
Peptic Ulcers
injection
Prostaglandins
Inhibits the secretion of HCl in the stomach
Erectile Dysfunction (Alprostadil)
H
Bronchial and Intestinal Smooth Muscle
Respiratory Symptoms
1
↓ Lung Capacity
Contraction
↑ NO
Intestinal Cramps
↑ Production of Nasal and Bronchial Mucus
Diarrhea
Stimulates Itch and Pain and Sensory Nerve
Endings
↑ Gastric HCl secretion
H
2
↓ Systemic BP
H
and H
1
2
Histamine
↓ Peripheral Resistance
Positive Inotropic (H
and H
)
1
2
Positive Chronotropic (H
)
2
Capillary Permeability
Vasodilation
Triple Response - Wheal Formation, Reddening
and Halo
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