Pharmacology Drug Chart Page 3
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18Pharmacology Drug Chart Page 3
Ganglionic and Neuromuscular Blockers
Drug Name
Receptor
Therapeutic Uses
Adverse Effects
Low Dose - Ganglionic stimulation by
Irritability and Tremors
depolarization
Intestinal Cramps and Diarrhea
↑ HR
High Dose - Ganglionic blockade
Nicotine
↑ BP
Sympathetic Stimulation followed by paralysis of
↑ Rate of Metabolism of other drugs - Induction
the ganglia
Competitive
Used for the emergency lowering of BP
Hexamethonium
Nicotinic Ganglionic
(Trimethaphan)
Blocker
Nondepolarizing NM
Low Dose - Nicotinic Receptor and
Histamine Release
Blocker
competitively blocks the binding of ACh
Ganglionic Blockade
↓ BP
High Dose - blocks the Ion Channels of the End
Tubocurarine
Plate
Used to relax skeletal muscle during surgery
Depolarizing NM
Rapid endothelial intubations
Hyperthermia
Succinylcholine
Blocker
Apnea due to the paralysis of the Diaphragm
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