Pharmacology Drug Chart Page 9
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18Pharmacology Drug Chart Page 9
Antiarrhythmic Drugs
Drug Name
Receptor
Therapeutic Uses
Adverse Effects
Binds to Open and
Slows Phase 0 Depolarization
May cause SA and AV Block
Quinidine
Inactive Na Channels
Treatment of Atrial, AV, and Ventricular
Asystole
Class IA
to Prevent Influx
Arrhythmias
May induce ventricular Tachycardia
+
Na
Channel Blocker
Binds to Open and
Shortens Phase 3 Repolarization
Drowsiness
Inactive Na Channels
Suppresses arrhythmias caused by abnormal
Slurred Speech
to Prevent Influx
automaticity within the cells
Agitation
Treatment of Ventricular Arrhythmias during MI
Confusion
Lidocaine
Drug of choice for the emergency treatment of
Convulsions
Class IB
Cardiac Arrhythmias - Wide therapeutic to toxic
Ventricular Arrhythmias
+
Na
Channel Blocker
ratio
Does not slow down conduction therefore it is
not useful for AV junction arrhythmias
Binds to Open and
Markedly Slows Phase 0 Depolarization
Negative Inotropic
Inactive Na Channels
Treatment of Refractory Ventricular
Can aggravate CHF
Flecainide
to Prevent Influx
Arrhythmias
Ventricular Tachycardia
Class IC
Dizziness
+
Na
Channel Blocker
Blurred Vision
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